New Products from Enzo Life Sciences

September 2009

View all the New Products on our Website                            NEW Antibodies Section

Proteasome ELISA Kit - A new kit for quantifying proteasome concentrations
Circulating and cellular proteasome levels have been reported to be elevated in a number of diseases, including multiple myeloma and systemic lupus. The new kit provides the means to quantify proteasome concentrations in biological samples using a Sandwich ELISA technique. Sample proteasome levels are determined by comparison to a 20S proteasome calibration curve produced in parallel. This kit provides sufficient material for a single 96 well plate.
LIT: M. Wada, et al.; J. Lab. Clin. Med. 121, 215 (1993) • K. Egerer, et al.; J. Rheumatol. 29, 2045 (2002) • C. Jakob, et al.; Blood. 109, 2100 (2007) • M. Majetschak & L. T. Sorell; J. Immunol. Methods. 334, 91 (2008)
Related Products: Browse complete listing of proteasome reagents

FluoForte™ Calcium Assay Kit – Brilliant results for calcium discovery
Monitor calcium mobilization in live cells with the brightest and most sensitive fluorescent Ca²⁺ indicator on the market. The FluoForte™ Calcium Assay Kit has the largest assay window to generate stronger green fluorescence signal than other calcium indicators. The homogeneous mix-and-read, no-wash kit is applicable to analyzing both GPCR (G protein-coupled receptor) and calcium ion channel targets. Suitable for high throughput screening.

Related Products: FluoForte™ Calcium Assay Kit (high-throughput) / FluoForte™ Reagent (5 x 50 µg) / FluoForte™ Reagent (1 mg)

DLL1 [Delta-like Protein1], Soluble (human) ELISA Kit
For the quantitative determination of soluble DLL1 in human serum, plasma or cell culture supernatant. Does not cross-react with mouse or rat sera. DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis.
Related Products: PAb to DLL1 (human) / PAb to DLL1 (human) / MAb to DLL1 (human) (D1L156-6) / DLL1 (human) (rec.) / DLL1 (human): Fc (human) (rec.)

Adiponectin (Globular Domain) (dog) (rec.)
Related Products: Adiponectin (dog) (rec.) / Adiponectin (human) (rec.) / Adiponectin (mouse) (rec.) / Adiponectin (rat) (rec.)

Cathepsin V Proenzyme (human) (rec.) (His) – An important protease involved in cancer and atherosclerosis
Recombinant glycosylated procathepsin V cloned from human cDNA and purified as full-length proenzyme. One step activation.
Related Products: Z-VVR-AMC (Fluorogenic Substrate) / All cathepsin products

ADAM Substrate (Fluorogenic)
Quenched fluorogenic substrate for ADAM8, -10, -12, -17 (TACE) and likely other ADAMs. Also efficiently cleaved by MMP-1, -2, -3, -8, -9, -13, and -14.
Related Products: All ADAM products / All MMP products

Boc-Ala-Ala-Nva-SBzl (Chromogenic Substrate) - A sensitive substrate for leukocyte proteinase 3
Also suitable for neutrophil elastase, granzyme H, cathepsin G, chymotrypsin, and rat MCPI and II.
Related Product: Proteinase 3 (human) (neutrophil)

(S)-ESBA - A new KAT II inhibitor
Potent and selective mouse/rat kynurenine aminotransferase II (KAT II) inhibitor, which reduces kynurenic acid (KYNA) production. Plays an important role in neurobiology by enhancing extracellular dopamine levels.
LIT: F. Rossi, et al.; Curr. Opin. Struct. Biol. 18, 748 (2008) • L. Amori, et al.; Neuroscience 159, 196 (2009)
Related Product: Kynurenic acid

MAb to FTO (FT403-2)
The FTO (fat mass and obesity-associated) gene is well conserved and found in a single copy in vertebrate species. It is suggested that the FTO protein plays a role in fat cell lipolysis, which may be important in explaining why the FTO gene (and FTO gene variants) is implicated in body weight regulation.
Related Products: FTO (human) (rec.) (His) / FTO (mouse) (rec.) (His) / PAb to FTO (human) / PAb to FTO (mouse) / MAb to FTO (human) (FT86-4) / FTO (human) (IntraCellular) ELISA Kit

MAb to Progranulin (mouse) (PG319-1)
Progranulin (PGRN), a widely expressed pluripotent growth factor, has been shown to be involved in many processes, such as wound repair, inflammation, and tumorigenesis. Further, mutations in the PGRN gene have been identified in cases of frontotemporal degeneration (FTD).
Related Products: Progranulin (mouse) ELISA Kit / Progranulin (mouse) (rec.) / MAb to Progranulin (human) (PG359-7) / Progranulin (human) ELISA Kit / Progranulin (human) (rec.)

MAb to c-IAP1 (1E1-1-10)
c IAP1 is one of eight identified human inhibitor of apoptosis proteins (IAPs) and is known to inhibit specific caspases. The antibody recognizes human and mouse c-IAP1.
LIT: J. Silke, et al.; PNAS 102, 16182 (2005) • J.E. Vince, et al.; Cell 131, 682 (2007) • J.E. Vince, et al.; J. Cell. Biol. 182, 171 (2008)
Related Product: PAb to c-IAP1

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Visit us at Conferences

2nd International Symposium on Cancer Biology, September 2-3, Belfast (UK)
2nd EMBO Conference on Ubiquitin & Ubiquitin-like Modifiers, September 22-26, Riva del Garda (Italy)
17th ECDO Euroconference: Destruction, Degradation & Death, Cell Death Control in Cancer & Neurodegeneration, September 23-26, Paris (France)
Signal Transduction & Disease, September 27-30, Aachen (Germany)
NCRI Meeting, October 4-7, Birmingham (UK)
NIH Research Festival, October 8-9, Bethesda (Maryland)
MipTec 2009, October 13-15, Basel (Switzerland)
Protein Modification in Development & Diseases, October 17, Liège (Belgium)
Neuroscience 2009, October 17-21, Chicaco (Illinois)
EMBO Autophagy, Cell Biology, Physiology & Pathology, October 18-21, Ascona (Switzerland)