Key tools for studying phosporylation events

By Tom Vendelbo: 10.01.07 in Drug discovery research

Phospho-specific antibodies are the new key tools for studying phosphorylation events.

Quote from Bethyl Laboratories product update for December:

X-ray repair cross-complementing gene I protein (XRCC1) in complex with DNA polymerase beta, DNA ligase III, and poly(ADP-ribose) polymerase is important in the base excision repair process.

Anti-Phospho XRCC1 (S485/T488) is only one of over 60 antibodies Bethyl Laboratories offers in their portfolio of polyclonal antibodies to phosphorylated proteins.

Phospho-specific antibodies have emerged as key tools for studying phosphorylation events. These antibodies are directed specifically against phosphorylated proteins. The key attribute is that they do not recognize the unphosphorylated form of the protein.

See the complete list of phospho-specific antibodies.